CONTRAVE®
FDA-Approved Weight Loss Medication

What is CONTRAVE® and how does it cause weight loss?

CONTRAVE® (naltrexone/bupropion) is an FDA-approved prescription pill that promotes weight loss by targeting the brain's appetite and reward centers, reducing hunger AND emotional cravings.

Unlike GLP-1 injections that work in the gut, CONTRAVE® works directly in the brain. Bupropion activates neurons in the hypothalamus that regulate appetite and energy expenditure, while naltrexone blocks the reward pathway that drives emotional and compulsive eating. Clinical studies showed patients using CONTRAVE® with diet and exercise achieved significantly greater weight loss than diet and exercise alone, and results were sustained over one year. Both active ingredients have well-established safety profiles with over 30 years of prescribing history.

Who is a candidate for CONTRAVE®?

• Adults with BMI ≥30 (obesity)
• Adults with BMI ≥27 with weight-related conditions (diabetes, hypertension, dyslipidemia)
• Those who struggle with emotional or stress eating
• Patients seeking an oral alternative to injections
• Patients who have not responded to diet and exercise alone

Who is NOT a candidate for CONTRAVE®?

• History of seizure disorder or eating disorder (bulimia)
• Current use of bupropion products (Wellbutrin, Zyban, Aplenzin)
• Current opioid use or opioid dependence treatment
• Uncontrolled hypertension
• Pregnancy, nursing, or planning to become pregnant
• Kidney or liver dysfunction

Why patients choose Florida Aesthetics

• Physician-prescribed and supervised
• Oral pill, no injections required
• Addresses emotional and stress eating specifically
• Regular monitoring and dose adjustment
• Combined with nutritional and lifestyle guidance